This post covers basic tmux configuration, enabling mouse support, changing pane key bindings, reloading the tmux config, and adjusting window and pane index settings.
You can checkout my config file
# Change prefix key to Ctrl + a
unbind C-b
set -g prefix C-a
bind C-a send-prefix
# Enable mouse support
set -g mouse on
# Enable Vim-style copy mode
setw -g mode-keys vi
bind-key -T copy-mode-vi v send -X begin-selection
bind-key -T copy-mode-vi y send -X copy-selection-and-cancel
bind-key -T copy-mode-vi Escape send -X cancel
bind -n M-v copy-mode
# Vim-style pane navigation
bind h select-pane -L
bind j select-pane -D
bind k select-pane -U
bind l select-pane -R
# Reload tmux config without restarting
bind r source-file ~/.tmux.conf
# Create a new window in the current directory
bind c new-window -c "#{pane_current_path}"
# Split panes in the current directory
bind | split-window -h -c "#{pane_current_path}"
bind - split-window -v -c "#{pane_current_path}"
# Unbind default split keys
unbind '"'
unbind %